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LACTIN 

(Lactose Intolerance) 

qPCR SNP Detection Kit

LACTIN (Lactose Intolerance) qPCR SNP Detection Kit

Description

The MCM6 gene is responsible for the production of the enzyme that metabolizes lactose. Depending on the type of MCM6 gene you have, a specific level of this enzyme is produced, which affects the digestion of lactose by the body.

REF. NUMBER

755SNP451pLC

PREDISPOSITION

Lactose Intolerance

ANALYSED GENE

MCM6

IDENTIFIED POLYMORPHISMS

rs4988235, rs182549

KIT CONTENTS

2 × Nuclease-Free Water
2 × 2xSNP MasterMix
2 × Oligos Set
2 × Positive Control Set

QUANTITY

100 rxns

STORAGE CONDITIONS

-25°C to -15°C

CERTIFICATES

More Information

Did you know...?

Lactose intolerance is a common condition that makes everyday life difficult. Prevalence among adults is up to 70% in Europe and as much as 80-100% in Asia and Africa. The main cause of lactose intolerance is a congenital lack of the lactase enzyme. The first symptoms can be seen around the age of 2, but the incidence increases with age. This ailment is most often diagnosed in adolescence and in adults.

Why is it important to know about food intolerance?

In addition to congenital lack of lactase (alactasia) or deficiency (hypolactasia) of the lactase enzyme, lactose intolerance may develop due to diseases that destroy the epithelium and intestinal villi responsible for the production of lactase, this condition is referred to as secondary or acquired intolerance. Depending on the degree of intolerance, symptoms appear from a few minutes to 2 hours after consuming a dairy product. The characteristic symptoms include: nausea, flatulence, intestinal flooding, feeling of fullness, intestinal colic, low pH of the feces.

How the test is performed?

To determine the genetic predisposition to lactose tolerance, we check 2 polymorphisms of the MCM6 gene. SNP analysis using our reagents is fast and accurate. Thanks to the IFU instructions included in the kit, the technician can easily interpret the results. The reaction lasts about 2 hours, and the temperature-time profile is selected so that the laboratory can analyze several genes simultaneously using one device. Ready-to-use reagents are included in the kit. It is enough for the lab technician to add each of them in the right proportion and the reaction is ready. Quickly, easily and professionally.

Why is it worth doing a genetic test?

Every day another person experiences discomfort, pain or problems with the digestive system. To check whether his situation is due to lactose intolerance, genetic testing will be the best method. They are accurate and fast and give a clear indication of whether person can consume dairy. The development of technology and knowledge allows us to easily find substitute products, e.g. plant-based drinks. However, to be sure whether it is worth giving up dairy products, it is recommended to perform a genetic test.

What can be done after the test result?

A professional approach to the client will inspire his trust and ignite the desire to learn about other genes. Discomfort or abdominal pain can have various causes. It is worth checking for the presence of various genetic mutations to have a broader view of your health. Without the need for sequencing, you can access information about many DNA fragments that affect key parameters of our lives.