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With the development of civilization and technological advances, the length of human life has increased considerably. There are also more hazards caused by environmental factors that lead to illnesses or disturbances in the human body. An irregular or unhealthy lifestyle is mainly responsible for the emergence of cardiovascular diseases and chronic diseases.

A number of risks and vulnerabilities are genetically determined and an appropriate study allows identification of individual predispositions of the organism in question to a specific disorder. By knowing the results of such a study, you can change your lifestyle accordingly and take preventive prophylaxis against illness.

Alzheimer's disease

Alzheimer's disease begins to interact with humans long before the onset of the first symptoms. Its effect leads to the atrophiness of brain nerve cells and connections between them as a result of reducing the volume of the brain.

What are the symptoms?

The classic development of the disease can start long before the onset of the first symptoms, which are most often cognitive impairment. The sick begins to have problems with short-term memory. As the disease progressions, there are disturbances in the exercise of simple daily activities and problems with the correct use of words or their forgetting.

What genes are analysed in the study and what do they influence?

The study examines two genes: APOE and TREM2, which are associated with Alzheimer's disease. The APOE gene plays an important role in the lipid and soluble lipid compounds that are energy substances for the brain. It participates in the transport of lipids from the blood to brain cells and in the removal of excess lipids from the central nervous system by the cerebrospinal fluid. Having a negative variant of the gene is the strongest genetic risk factor for Alzheimer's disease and is associated with impaired cerebral metabolism and cerebral vascular function. The TREM2 gene encodes the formation of a protein affecting the functioning of microglia by supporting the survival of its cells and promoting its growth. Mikroglej is the first line of immune defense in brain diseases. When a stimulant appears, its cells (normally at rest) begin to "monitor" the tissue environment, repair damaged neurons and remove dead ones. Decreased protein activity due to mutation in the TREM2 gene can lead to brain damage by microglia inability to function properly and consequently to the development of Alzheimer's disease.

Who is recommended to perform the test?

The result of a genetic test performed at a young age can give indications of a change in lifestyle and to attach greater importance to the occurrence of possible symptoms in later years. The study is recommended to anyone who wants to take care of themselves and reduce the likelihood of developing the disease.

Can I donate this study to someone?'

You can transfer/donate selected studies to another person. You just need to enter the box names for each of the selected products when completing your order after entering your shipping address. By giving different names of boxes (e.g. 1-my, 2-for-mum) You can create test kits for both yourself and the people you want to donate GeneMe study to.

It is also worth remembering that:

Each successive test within one SWAT (i.e. one box) is awarded for 50% of the price.
We send your entire order to one of the specified addresses to send the boxes in different places to separate orders.

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