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ALLPEA 

(Peanut Allergy) 

qPCR SNP Detection Kit

ALLPEA (Peanut Allergy) qPCR SNP Detection Kit

Description

Analysed gene plays a key role in hereditary peanut allergy. Changes in the HLA-DRA gene are associated with an increased susceptibility to the development of peanut allergies, especially among people of European origin.

REF. NUMBER

755SNP451pAP

PREDISPOSITION

Peanut Allergy

ANALYSED GENE

HLA-DRA

IDENTIFIED POLYMORPHISM

rs7192

KIT CONTENTS

1 × Nuclease-Free Water
1 × 2xSNP MasterMix
1 × Oligos Set
1 × Positive Control Set

QUANTITY

100 rxns

STORAGE CONDITIONS

-25°C to -15°C

CERTIFICATES

More Information

Did you know...?

240 million people worldwide are allergic to nuts. Food allergy (especially nuts allergy) is a growing health problem that affects ∼8% of children worldwide. Genetic factors seem to play a leading role in the development of FA, though interaction with environmental factors cannot be excluded. The broader network of genetic loci mediating the risk of this complex disorder remains to be identified.

What may happen?

An allergy to nuts or peanuts can lead to a life-threatening anaphylactic shock (anaphylaxis). That is why it is so important to properly diagnose allergies and educate yourself about avoiding allergenic allergens, as well as managing anaphylaxis. Symptoms of an allergic reaction appear a few minutes after eating a nut (immediate reaction). They depend on the ingested dose of the sensitizing food. Large doses usually cause more severe allergic reactions (mainly after ingestion of food, much less frequently through contact with the skin). They are often manifested by itching in the mouth and swelling of the lips.

How the test is performed?

The mutation in HLA-DRA gene increases susceptibility to peanut allergy. SNP analysis using our reagents is fast and accurate. Thanks to the IFU instructions included in the kit, the technician can easily interpret the results. The reaction lasts about 2 hours, and the temperature-time profile is selected so that the laboratory can analyze several genes simultaneously using one device. Ready-to-use reagents are included in the kit. It is enough for the lab technician to add each of them in the right proportion and the reaction is ready. Quickly, easily and professionally.

Why is it worth doing a genetic test?

Based on the test result and the decision matrix in the product IFU, the client will receive precise information about their gene variant and a brief explanation concerning what this variant means. Based on the product IFU the service provider can comply a report with the result and recommendations tailored to the client’s genotype.

What can be done after the test result?

A professional approach to the client will inspire his trust and ignite their desire to learn about other genes. Without the need for sequencing, clients can access information about many DNA fragments that affect key parameters of their lives.