ANLO
(Androgenetic Alopecia)
qPCR SNP Detection Kit
Description
The HDAC4 gene plays a key role in regulating the communication of androgen receptors and altering the sensitivity of the receptor to dihydrotestosterone (DHT). A mutation in this gene may contribute to the accelerated process of baldness.
REF. NUMBER
755SNP451pal
PREDISPOSITION
Androgenetic Alopecia
ANALYSED GENE
HDAC4
IDENTIFIED POLYMORPHISM
rs9287638
KIT CONTENTS
1 × Nuclease-Free Water
1 × 2xSNP MasterMix
1 × Oligos Set
1 × Positive Control Set
QUANTITY
100 rxns
STORAGE CONDITIONS
-25°C to -15°C
CERTIFICATES
More Information
Did you know...?
Androgenic alopecia (AGA), also called male pattern baldness, is an inherited disease caused by many genes. Androgens can cause hair follicles to enlarge in the area of the chin, armpits and intimate areas, and on the scalp, their miniaturization and, consequently, baldness.
Why is it worth knowing your genetic predisposition to baldness?
Genetic testing will allow you to assess the risk of baldness in the future. The disease varies in severity and affects both men and women of all ages. In men, hair loss occurs at the temples and / or the top of the head, and in women, hair is thinned all over the scalp. Androgenetic alopecia affects approximately 40% of women under the age of 40 and over 80% of men under the age of 80.
How the test is performed?
The HDAC4 gene plays a key role in the regulation of androgen receptor transmission. SNP analysis using our reagents is fast and accurate. Thanks to the IFU instructions included in the kit, the technician can easily interpret the results. The reaction lasts about 2 hours, and the temperature-time profile is selected so that the laboratory can analyze several genes simultaneously using one device. Ready-to-use reagents are included in the kit. It is enough for the lab technician to add each of them in the right proportion and the reaction is ready. Quickly, easily and professionally.
Why is it worth doing a genetic test?
Knowing their genotype, the client will be able to recognize the cause of their problems with baldness. Having a high risk of baldness, the clients can pass the gene mutations on to their children. Together with the result, the client will receive recommendations.
What can be done after the test result?
A professional approach to the client will inspire his trust and ignite the desire to learn about other genes. Without the need for sequencing, you can access information about many DNA fragments that affect key parameters of our lives.