CARDI
(Cardiovascular Diseases)
qPCR SNP Detection Kit
Description
Analysed genes play a key role in the transport and metabolism of lipids and in the maintenance of normal blood pressure. These mutations contribute to the development of diseases such as atherosclerosis, coronary artery disease or heart attack.
REF. NUMBER
755SNP451pcd
PREDISPOSITION
Cardiovascular Diseases
ANALYSED GENES
LPA, AGT, NOS3
IDENTIFIED POLYMORPHISMS
rs10455872, rs699, rs3798220, rs2070744
KIT CONTENTS
4 × Nuclease-Free Water
4 × 2xSNP MasterMix
4 × Oligos Set
4 × Positive Control Set
QUANTITY
100 rxns
STORAGE CONDITIONS
-25°C to -15°C
CERTIFICATES
More Information
Did you know...?
The circulatory system is the system that carries oxygen – and nutrient-rich blood throughout the body while draining harmful waste products from the tissues. This system consists of the heart and the blood vessels – arteries, veins, and capillaries. Major cardiovascular diseases causing premature death: atherosclerosis, coronary artery disease (also called ischemic), heart attack, stroke, hypertension, peripheral vascular diseases; chronic heart failure; cardiac rhythm disturbances.
What is the prevalence of cardiovascular diseases?
According to the report published by The European Heart Network in 2017, cardiovascular diseases are the main cause of mortality in the European population, responsible for more than 3.9 million deaths annually, which is 45% of all deaths in Europe. In men, cardiovascular diseases cause 40% of all deaths, while they account for 49% of deaths in women. Cardiovascular diseases are the main cause of premature death (under 65) in Europe, where they account for approximately 667,000 deaths per year (29% of all deaths under 65).
How the test is performed?
Cardiovascular diseases have a genetic background. LPA, AGT and NOS3 genes are DNA fragments that contain instructions for building proteins that play a significant role in lipoprotein metabolism and control the volume of circulating blood in the body. For the analysis of LPA, AGT nad NOS3 gene polymorphisms, the real-time PCR molecular method is used, which enables precise determination of the genotype.
How will the client benefit?
Interpretation of the obtained results, based on the IFU of the product included in the kit, allows for the preparation of a detailed report containing both the genotype description and recommendations indicating the further diagnostic path. The test we offer is relatively quick, uncomplicated and does not require complicated lab work.
Why is it worth doing a genetic test?
The offered test gives a susceptible individual a chance to implement preventive measures and avoid premature death. Professional approach to the patient and detailed interpretation of the result along with recommendations will encourage the client to take advantage of the laboratory’s offer and do other genetic tests.
What can be done after the test result?
In the case of an unfavorable variant of the gene, it is important to follow the recommendations and consult a doctor. It should be remembered that a normal genotype does not exclude the disease. The great potential of genetic testing makes it possible to predict many diseases and provides the patient with an opportunity to take action to improve their health.