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DEVI 

(Vitamin D Metabolism) 

qPCR SNP Detection Kit

DEVI (Vitamin D Metabolism) qPCR SNP Detection Kit

Description

Analysed genes are responsible for the metabolism and transport of vitamin D in the body. Adverse changes in these genes may predispose to ineffective vitamin D metabolism.

REF. NUMBER

755SNP451pDV

PREDISPOSITION

Vitamin D Metabolism

ANALYSED GENES

CYP2R1, GC

IDENTIFIED POLYMORPHISMS

rs10741657, rs2282679

KIT CONTENTS

2 × Nuclease-Free Water
2 × 2xSNP MasterMix
2 × Oligos Set
2 × Positive Control Set

QUANTITY

100 rxns

STORAGE CONDITIONS

-25°C to -15°C

CERTIFICATES

More Information

Did you know...?

Vitamin D3 is produced in human skin as a result of UVB radiation (sun, UV lamps). It is the most important source of this vitamin and accounts for approximately 80% of the requirement. The rest is complemented by natural food products. Most Europeans show an insufficient intake of vitamin D, which in the absence of adequate exposure to UVB radiation may pose a high risk of vitamin D deficiency and its health consequences. In Central and Northern Europe, from October to March, the wavelength of radiation is too low and there are too few hours of sunshine per day for the body to produce enough vitamin D.

Why is it important to know about vitamin D metabolism?

Vitamin D deficiency symptoms are: bone pains, muscle aches, rapid fatigue, insomnia, diarrhea, periodontal disease, appetite problems, hypertension. The knowledge of a reduced metabolism will help to avoid these symptoms and, when they appear, will help to reduce them.

How the test is performed?

The CYP2R1 and GC genes are DNA fragments that contain instructions for building proteins that are involved in the metabolism of vitamin D. SNP analysis using our reagents is fast and accurate. Thanks to the IFU instructions included in the kit, the technician can easily interpret the results. The reaction lasts about 2 hours, and the temperature-time profile is selected so that the laboratory can analyze several genes simultaneously using one equipment. Ready-to-use reagents are included in the kit. It is enough for the lab technician to add each of them in the right proportion and the reaction is ready, quickly, easily and professionally.

Why is it worth doing a genetic test?

Nowadays, most clients work in offices, in front of the computer, not having the opportunity to go out for fresh air. Outside, smog prevents the sun’s rays from reaching our skin. If the client’s genes show also lower vitamin D metabolism, the effects can be very serious. Therefore, in order to encourage the client to perform the test, it is necessary to inform him about them and thanks to the recommendations contained in the IFU, you can show the client what they should do to optimize their vitamin D levels.

What can be done after the test result?

A professional approach to the client will inspire his trust and ignite the desire to learn about other genes. It is worth checking for the presence of various genetic mutations to have a broader view of your health. Without the need for sequencing, you can access information about many DNA fragments that affect key parameters of our lives.