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MECH 

(Cholesterol Metabolism) 

qPCR SNP Detection Kit

MECH (Cholesterol Metabolism) qPCR SNP Detection Kit

Description

The APOE gene is responsible for the metabolism of Cholesterol and thus its overall concentration in the body. The consequence of abnormalities in the cholesterol economy may be: atherosclerosis, coronary artery disease, heart attack or stroke.

REF. NUMBER

755SNP451pMH

PREDISPOSITION

Cholesterol Metabolism

ANALYSED GENE

APOE

IDENTIFIED POLYMORPHISMS

rs429358, rs7412

KIT CONTENTS

3 × Nuclease-Free Water
3 × 2xSNP MasterMix
3 × Oligos Set
3 × Positive Control

QUANTITY

100 rxns

STORAGE CONDITIONS

-25°C to -15°C

CERTIFICATES

More Information

Did you know...?

According to the World Health Organization (WHO), 17.5 million people die annually from cardiovascular diseases. This means that this group of diseases is the most important and common cause of human mortality in the world. High blood cholesterol is a major risk factor for cardiovascular disease. Cholesterol occurs in the body in a form related to polypeptides: HDL, or high-density lipoprotein (good cholesterol), LDL, or low-density lipoprotein (bad cholesterol).

Why knowledge about cholesterol metabolism is important?

Having knowledge about the body’s ability to convert cholesterol is extremely important. High cholesterol leads to atherosclerosis, high blood pressure, ischemic stroke, heart attack. Ultimately, it can be the cause of death. Therefore, it is worth checking whether we have a genetic predisposition to hypertriglyceridemia.

How the test is performed?

The qPCR test can detect mutations in the ApoE gene. SNP analysis using our reagents is fast and accurate. Thanks to the IFU instructions included in the kit, the technician can easily interpret the results. The reaction lasts about 2 hours, and the temperature-time profile is selected so that the laboratory can analyze several genes simultaneously using one equipment. Ready-to-use reagents are included in the kit. It is enough for the lab technician to add each of them in the right proportion and the reaction is ready. Quickly, easily and professionally.

What can be done after the test result?

A professional approach to the client will inspire his trust and ignite the desire to learn about other genes. Without the need for sequencing, you can access information about many DNA fragments that affect key parameters of our lives. After obtaining the result showing an increased risk of high cholesterol, it is worth performing additional genetic tests – the risk of hypertension, cardiovascular diseases, the risk of obesity.