SKIMO
(Skin Moisture)
qPCR SNP Detection Kit
Description
The AQP3 gene is key in skin moisture. The gene is responsible for the efficient transport of water and glycerol between skin cells. Unfavourable changes in this gene result in decreased hydration of the epidermis.
REF. NUMBER
755SNP451psm
PREDISPOSITION
Skin Moisture
ANALYSED GENE
AQP3
IDENTIFIED POLYMORPHISM
rs1755371
KIT CONTENTS
1 × Nuclease-Free Water
1 × 2xSNP MasterMix
1 × Oligos Set
1 × Positive Control Set
QUANTITY
100 rxns
STORAGE CONDITIONS
-25°C to -15°C
CERTIFICATES
More Information
Did you know...?
Water constitutes about 50-60% of the body mass, therefore the correct regulation of homeostasis is crucial for the proper functioning of living creatures. The main role in maintaining proper homeostasis is played by aquaporins (AQPs), i.e. water protein channels that enable the transport of water through cell membranes.
Why knowledge about skin moisture is important?
When it comes to skin hydration, AQP3 is the key aquaporin. It occurs in the basal layer of the epidermis. Increased expression of AQP3 is associated with the skin’s response to stress or chemicals. Aquaporin 3 is an important determinant of epidermal proliferation as well as skin cancer development. The outermost layer of the skin, the stratum corneum (SC), consists of keratinocytes that pass from the lower layer of the skin during development. Moisturizing the stratum corneum affects its properties – reduced hydration is associated with age or skin diseases.
How the test is performed?
The AQP3 gene is a DNA fragment that contains instructions for the construction of proteins that are involved in the transport of water across cell membranes. SNP analysis using our reagents is fast and accurate. Thanks to the IFU instructions included in the kit, the technician can easily interpret the results. The reaction lasts about 2 hours, and the temperature-time profile is selected so that the laboratory can analyze several genes simultaneously using one device. Ready-to-use reagents are included in the kit. It is enough for the lab technician to add each of them in the right proportion and the reaction is ready. Quickly, easily and professionally.
Why is it worth doing a genetic test?
In the era of increasing care for appearance, people want to know the genetic predisposition in this topic. Before they use aesthetic medicine, they will be able to learn about their DNA.
What can be done after the test result?
A professional approach to the client will inspire his trust and ignite the desire to learn about other genes. Without the need for sequencing, you can access information about many DNA fragments that affect key parameters of our lives.