Home > Products > SNPs > VIBE (Vitamin B12 Metabolism)


(Vitamin B12 Metabolism) 

qPCR SNP Detection Kit

VIBE (Vitamin B12 Metabolism) qPCR SNP Detection Kit


The FUT2 gene is responsible for production of an enzyme involved in the absorption of vitamin B12 in the small intestine and its transport between the cells in the human body. People with an unfavourable genetic variant have a higher risk of vitamin B12 deficiency, related to the malabsorption of this vitamin.




Vitamin B12 Metabolism






1 × Nuclease-Free Water
1 × 2xSNP MasterMix
1 × Oligos Set
1 × Positive Control Set


100 rxns


-25°C to -15°C


More Information

Did you know...?

Vitamin B12 plays an extremely important role in our body, and its correct level is essential for optimal human function. It has the largest structure of all vitamins, and its second name – cobalamin – is due to its cobalt content. It is a vitamin produced only with the participation of microorganisms. Because the body cannot make it on its own, we need to provide it with our food.

Why is it important to know about vitamin B12 metabolism?

Vitamin B12 is extremely versatile. It takes part in the production of nucleic acids and red blood cells, and is responsible for many metabolic reactions. Vitamin B12 deficiency affects many systems and causes a wide spectrum of symptoms:
- Cardiovascular symptoms – anemia, manifested by dizziness, pallor and shortness of breath, weakness or rapid heart rate and concentration disorders.
- Symptoms of the nervous system – there may be disturbances in the sense of hearing, smell or sensation, as well as movement disorders and characteristic dizziness.
- Gastrointestinal symptoms – loss of appetite and weight loss, nausea and taste disturbances, swelling and redness of the tongue.
- Symptoms of the skin – Vitamin B12 deficiency can result in vitiligo or a change in skin tone to pale yellow.

How the test is performed?

Mutations in the FUT2 gene have a significant impact on vitamin B12 level in the human body. Thanks to our reagents included in the kit, we can quickly and accurately determine the client’s genotype. The results are easy to interpret. In the included IFU, you can compare each curve and draw conclusions. In addition, in order to facilitate the work, we attach abbreviated recommendations corresponding to each genotype. The reagents are ready to use. Each stage of the test is described step by step in the manual. No sequencing is needed.

Why is it worth doing a genetic test?

Genetic tests make it possible to discover the causes of many common health and wellness conditions. As a result of the genetic test, the client can better understand their genetic make-up and the implications for their health and well-being.

What can be done after the test result?

A professional approach to the client will inspire his trust and ignite the desire to learn about other genes. It is worth checking for the presence of various genetic mutations to have a broader view of your health. Without the need for sequencing, you can access information about many DNA fragments that affect key parameters of our lives.