HUPA
(HPV 16/18)
qPCR Detection Kit
Description
The molecular test designed for identification of the Human papillomavirus (HPV) DNA. HPV is a pathogen belonging to Papillomaviridae family. The virus is transmitted mainly through sexual contact and causes changes to the skin and mucous membranes (throat, mouth, and genitals). Oncogenic types (high-risk HPV) are particularly dangerous because in the case of long-lasting infection they can lead to the development of cervical cancer. Nearly all cervical cancer is due to HPV and two strains – HPV16 and HPV18 – account for 70% of cases.
REF. NUMBER
755HSTHP00
PATHOGENE
HPV 16/18
KIT CONTENTS
1 × Nuclease-Free Water
1 × 2xMasterMix qPCR Probe
1 × Oligos Set
1 × Positive Control
QUANTITY
100 rxns
STORAGE CONDITIONS
-25°C to -15°C
CERTIFICATES
More Information
Did you know...?
HPV infection is caused by a DNA virus – Human papillomavirus from the Papillomaviridae family. The virus is transmitted mainly through sexual contact but also through sustained direct skin-to-skin contact. Occasionally it can spread from mother to her baby during pregnancy. Human papillomavirus infects epidermal and squamos epithelial cells. There are over 200 types of the virus. The types of HPV described as low-oncogenic, i.e. having a low potential to cause cancer, are types 6, 11, 40, 42, 43, 44, 54, 61, 72 and are responsible for the formation of skin and genital warts. Types 6 and 11 are responsible for the formation of condyloma. The oncogenic types are: 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59.
How serious is HPV
Most people who become infected with HPV do not know they have it. Usually, the body’s immune system gets rid of the disease. HPV sexually transmitted infection results in skin changes – warts, which are usually located in the genital area. The disease is dangerous especially for women because it may be associated with an increased risk of cervical cancer. Many HPV infections cause no symptoms and 90% resolve spontaneously within two years. The most serious consequence of long lasting HPV infection is development of dysplastic changes which over time lead to cervical cancer. That is why early diagnosis is of great importance.
How the test is performed?
HUPA test is based on the molecular method, during the course of which genetic material of Human papillomavirus is detected. Genetic material analysis is fast and accurate. Thanks to the ready-to-use reagents included in the kit, the preparation of the reaction mixture is quick and does not require extensive lab work. Interpretation of the obtained results is easy thanks to the product IFU included in the kit.
Why is it worth doing a genetic test?
Early detection of the virus especially high-risk type gives a chance to avoid development of cancer. If found early, abnormal cells can be treated before they become cancerous. It’s much easier to prevent cervical cancer than to treat it once it develops.
What can be done after the test result?
The test result should be consulted with a doctor who will implement the appropriate therapy. Also HPV vaccination should be considered for cervical cancer prevention. Moreover, patients infected with HPV must be aware of the risk of infection sexual partners and the possible need for appropriate periodic examinations (cytology, colposcopy).